A Rare Case of Congenital Hypothyroidism

Congenital Hypothyroidism (CH) is a common preventable cause of mental retardation. The incidence CH 1 in 2500 to 3000 newborns. Most causes are thyroid dysgenesis and dyshormonogenesis. Some disorder like maternal autoantibodies, intake anti medication, iodine deficiency or excess can result transient CH. Common symptoms include decreased activity increased sleep, feeding difficulty, constipation, prolonged jaundice. In this case report, A 3 day old baby was admitted SNCU with chief complain yellowish discoloration upto abdomen respiratory distress. On examination, signs myxedematous facies, large fontanels, macroglossia, distended umbilical hernia, hypotonia. Thyroid accounts for 85% permanent, primary CH, while inborn errors hormone biosynthesis (dyshormonogeneses) account 10-15% cases. Secondary central may occur isolated TSH deficiency, but more commonly it associated congenital hypopitiutarism. Transient most occurs preterm infants born.